If you still wish to use a pet meter, you will use the same reference numbers for making dosing decisions as you would with a human meter. But your vet can prescribe these under the 'cascade system'. It is manufactured by Boehringer Ingelheim and it “a sterile aqueous protamine zinc suspension of recombinant human insulin” notes Drugs.com.. ProZinc should not be administered to humans. Recently, a recombinant human PZI insulin licensed for use in cats (ProZinc®) has been released in the US; most likely, it will become available in other countries in the near future. PROZINC is an aqueous protamine zinc suspension of recombinant human insulin that is used to reduce high blood sugar (hyperglycemia) in cats with diabetes mellitus. 1. PROZINC should be given only to the cat for which it is prescribed. PROZINC is an aqueous protamine zinc suspension of recombinant human insulin that is used to reduce hyperglycemia (high blood glucose or high blood sugar) and clinical signs associated with hyperglycemia in cats and dogs with diabetes mellitus. Signs may include weakness, depression, behavioral changes, muscle twitching, and anxiety. Protamine zinc insulin formulations are classified as long-acting, with a typical duration of effect in the cat of 10-14 hours. Fortunately, following injection, PROZINC ® (protamine zinc recombinant human insulin) works to safely maintain a dog’s blood glucose levels throughout the day, allowing for convenient once daily dosing for most dogs. Each mL of ProZinc product contains 40 IU recombinant human insulin. ProZinc®is the first and only FDA-approved insulin for cats made from recombinant DNA (DNA molecules created from the DNA of two unrelated organisms) that is identical to human insulin. There are separate syringes manufactured for U-100 and U-40. Keep out of the reach of children. Generally U-100 syringes have an orange cap and U-40 syringes have a red cap. Call a physician immediately if you accidentally inject yourself with ProZinc. “Once-daily dosing with PROZINC is a breakthrough for pet owners … Boehringer Ingelheim unveiled a new presentation of PROZINC ® (protamine zinc recombinant human insulin) with the proven benefit of once-daily dosing in most canine diabetic patients.Now, with two presentations designed for feline and canine patients, PROZINC is the insulin veterinarians have been waiting for. If the wrong syringe type is used the cat can be dangerously over- or under-dosed. PROZINC ® (protamine zinc recombinant human insulin), the simple and reliable choice for diabetes control in dogs and cats. The international guidelines recommend the use of longer-acting insulins for cats; those are Prozinc, and the human insulins, Lantus and Levemir. ProZinc (aqueous suspension of protamine zinc recombinant human insulin) is an FDA-approved long-acting insulin for use in cats. This is a recombinant human PZI insulin specifically designed for cats, and it is incredibly safe and effective. If you chose to use ProZinc, it may only be available in U-40 strength (as opposed to the more common U-100 strength) and will require special U-40 syringes or use of a PROZINC (protamine zinc recombinant human insulin) is indicated for the reduction of hyperglycemia and hyperglycemia-associated clinical signs in cats with diabetes mellitus. It is indicated for the reduction of hyperglycemia and hyperglycemia-associated clinical signs in cats with diabetes mellitus. Human Insulin - Diabetes In Dogs: The K9diabetes.com Forum . The route of administration is subcutaneous. It's labelled as being developed just for cats, however, right off the bat, you can see that it's not the most ideal for cats because it is not "cat" insulin, it's not pork or beef insulin, it is human recombinant insulin. ProZinc insulin has long been prescribed for cats and administered at 12-hour intervals. Hello Everyone - I wanted to start a new thread on this subject so hopefully many will respond. Detemir is a human recombinant insulin available in the market as Levermir (manufactured by Novo Nordisk). What are the side effects of ProZinc Insulin for Dogs and Cats, 10 ml Vial? Description ProZinc® insulin is a sterile aqueous protamine zinc suspension of recombinant human insulin. ProZinc … ProZinc contains human insulin (rDNA) (INN: insulin, human), produced with recombinant DNA technology in the yeast Pichia pastoris , as a 40 IU/ml protamine zinc insulin suspension. So, a U40 syringe is actually 2 times less potent than a U100 syringe. DO NOT SHAKE OR AGITATE THE VIAL. Avoid contact with eyes. See Details . One is the U100 syringe, which is commonly found in the human market, and then there's a U40 syringe, which is commonly found in the veterinary market with insulin products like Vetsulin and ProZinc. Detemir. Do not give a dose of ProZinc to a pet experiencing an episode of low blood glucose (hypoglycemia). Dosage and Administration: USE OF A SYRINGE OTHER THAN A U-40 SYRINGE WILL RESULT IN INCORRECT DOSING. Dosage and Administration USE OF A SYRINGE OTHER THAN A U-40 SYRINGE WILL RESULT IN INCORRECT DOSING. Call a physician immediately if you accidentally inject yourself with ProZinc. Keep out of reach of children. Further information available in the SPC or from Boehringer Ingelheim Limited,Vetmedica, Bracknell, Berkshire, RG12 8YS, UK.Tel: +44 (0)1344 746959 (sales & marketing enquiries) or +44 (0)1344 746957 (technical enquiries). ProZinc (protamine zinc recombinant human insulin) is an injectable insulin for cats and insulin for dogs. PROZINC (protamine zinc recombinant human insulin) is for use in cats and dogs only. ProZinc stands for Protamine Zinc Human Recombinant Insulin. Lantus and Levemir are not licensed for use in cats. In case of accidental injection, seek medical attention immediately. THIS PRODUCT IS LIMITED TO 1 PER CUSTOMER. It works in a similar way … Description: PROZINC® is a sterile aqueous protamine zinc suspension of recombinant human insulin. Boehringer Ingelheim provides online resources at bit.ly/3bahzHW for dog owners who need help administering insulin shots at home. ProZinc should not be administered to humans. 5. 1,2 Get Code. A veterinarian must prescribe PROZINC for your cat. PROZINC should be … Owners should be advised to observe for signs of hypoglycemia (low blood sugar). How PROZINC Helps + just two daily doses a day in cats and once-a-day dosing in most dogs, delivered before or just after a meal, PROZINC provides fast, effective results for hyperglycemia in pets with diabetes. FOR SUBCUTANEOUS INJECTION ONLY. The correct dose is determined individually for each animal depending on weight and needs to be adjusted depending on the response to treatment. (ProZinc, although a human insulin, is marketed for pets, and as such is U-40.) Each mL contains: recombinant human insulin 40 International Units (IU) protamine sulfate 0.466 mg zinc oxide 0.088 mg glycerin 16.00 mg dibasic sodium phosphate, heptahydrate 3.78 mg phenol (added as preservative) 2.50 mg hydrochloric acid 1.63 mg water for … ProZinc® (protamine zinc recombinant human insulin) is an injectable insulin for cats and insulin for dogs. FOR SUBCUTANEOUS INJECTION ONLY. In case of contact, immediately flush eyes with running water for at least 15 minutes. ProZinc® (Protamine Zinc Recombinant Human Insulin) 926689 Version #: 03 Revision date: 03-June 2019 Issue date: 06-May-2015 SDS US 1 / 8 1. A preliminary study showed that good glycemic control was achieved in a substantial percentage of cats. ProZinc can only be obtained with a prescription and is available as a suspension for injection (40 IU/ml). You just pull the cap of the pen off and there's a rubber stopper just like on a vial. They are also 0.5 ml, while Prozinc is 0.3. Description: ProZinc® insulin is a sterile aqueous protamine zinc suspension of recombinant human insulin. We don't use the pens as they are supposed to be used in humans. IMPORTANT SAFETY INFORMATION: PROZINC is for use in dogs and cats only. FOR SUBCUTANEOUS INJECTION IN CATS ONLY. Dosage and Administration USE OF A SYRINGE OTHER THAN A U-40 SYRINGE WILL RESULT IN INCORRECT DOSING. Like other types of insulin, ProZinc carries a risk of side effects. If Prozinc becomes unavailable then the options for longer-lasting insulin are Lantus and Levemir. Compare Lantus Insulin to ProZinc Cat Insulin to Vetsulin Insulin Helps control blood glucose and alleviate symptoms of diabetes It is the first and only FDA-approved insulin for cats made from recombinant DNA (DNA molecules created from the DNA of two unrelated organisms) that is identical to human insulin The ingredients in ProZinc (protamine zinc insulin) are classified as long … ProZinc should not be used in dogs that are sensitive to protamine zinc recombinant human insulin or any other ingredients in ProZinc. You insert the insulin sy The U.S. Food and Drug Administration approved the use of ProZinc (protamine zinc recombinant human insulin) in dogs in early 2019. Each pen only holds 300 units so you can usually use every drop. I found few on VetUK, but they have U40 with different dosing - Prozinc have 12 units with 1/2 increments, and the ones at VetUK have 20 units per syringe, so I'm quite confused. PROZINC provides fast, effective results for dogs with diabetes. It is given as an injection under the skin twice daily for cats and once daily for dogs either at the same time or immediately after a meal. ProZinc contains protamine zinc recombinant human insulin. Now, there are two drug products specifically approved for the management of diabetes mellitus in dogs, ProZinc … However, veterinary endocrinologists do not recommend its use and promote ProZinc (manufactured by BoehringerIngelheim) instead. DO NOT SHAKE OR AGITATE THE VIAL. The product is presented in cartons of a single 10 ml type I glass vial. PROZINC … Keep out of the reach of children. In severe cases of hypoglycemia, seizures and coma can occur. ProZinc (protamine zinc recombinant human insulin) is indicated for the reduction of hyperglycemia and hyperglycemia-associated clinical signs in cats with diabetes mellitus. Email: vetmedica.uk@boehringer-ingelheim.com Date of preparation: Feb 2016.AHD9040. Use a meter calibrated for humans, not a pet-specific meter. Humans use special needles that attach to the pen. ProZinc has not been evaluated for use in humans. Identification Product identifier Other means of identification Synonyms Recommended use Recommended Nonerestrictions SAFETY DATA SHEET ProZinc® (Protamine Zinc Recombinant Human Insulin) Protamine Zinc Recombinant Human Insulin … Description ProZinc® insulin is a sterile aqueous protamine zinc suspension of recombinant human insulin. ProZinc insulin is sold only by vets. Indication: PROZINC (protamine zinc recombinant human insulin) is indicated for the reduction of hyperglycemia and hyperglycemia-associated clinical signs in dogs with diabetes mellitus. DO NOT SHAKE OR AGITATE THE VIAL. Diabetes Discussion: Your Dog Anything related to your diabetic dog. As already stated, ProZinc is long-acting insulin approved by the FDA for cats. Each mL contains: recombinant human insulin 40 International Units (IU) protamine sulfate 0.466 mg zinc oxide 0.088 mg glycerin 16.00 mg dibasic sodium phosphate, heptahydrate 3.78 mg phenol (added as preservative) 2.50 mg hydrochloric acid 1.63 mg water for … Some vets do not know this. The target species is cats and the product is for use in animals with diabetes mellitus . We use regular insulin syringes and just pull the insulin out of the pen (like they are "mini-vials"). I would like to know if anyone started out using Vetsulin and ended up changing to human insulin for better control. UK: POM-V IE: POM. Reference numbers given are for measuring blood glucose with a human meter. Do not give a dose of ProZinc to a pet experiencing an episode of low blood glucose (hypoglycemia). Her Prozinc syringes are running out and I was looking for a substitute here in UK, as the Prozinc ones are £46. ProZinc® (protamine zinc recombinant human insulin) abcd Caution: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Accidental injection may cause hypoglycemia.